Will Actos Be the Next Avandia?
Actos is the previously number one selling diabetes medication used by people with Type 2 diabetes to control their blood sugar. Avandia was also once the number one diabetes drug in the US, which has been in the news much more in recent years for having caused heart attacks and strokes than for its sales figures. In fact, it was Avandia’s withdrawal from the market that led to the rise of Actos. Avandia was also the subject of numerous FDA bulletins and safety warnings, but ultimately the agency acted far too late in its restriction of Avandia. The FDA linked Avandia use to over 83,000 heart attacks and there have been more than ten thousand Avandia lawsuits. That may now be true for Avandia as it has been linked to a greater than usual risk for bladder cancer. The Actos bladder cancer risk has resulted in the regulatory agencies in France and Germany suspending the use of Actos; it went on to be voluntarily recalled in France. Since this action this past June, along with a second FDA Actos bladder cancer warning, there have been a flurry of Actos bladder cancer lawsuits filed. These lawsuits all allege that the drug’s manufacturer was aware that Actos increased bladder cancer risks from its earliest tests. While these allegations are certainly serious, they are nothing new when it comes to diabetes medications. The top selling diabetes drug in the United States is virtually guaranteed revenues of more than $2.5 billion a year and similar charges were leveled at the maker of Avandia and resulted in thousands of Avandia lawsuits.